Saturday, May 10, 2008
| Scientific Foundations Of Clinical Practice,part2 Scientific Foundations of Clinical Practice, Part II Pediatric Clinics of North America Hardcover: 240 pages Publisher: Saunders; 1 edition (October 27, 2006) Language: English ISBN-10: 1416038973 ISBN-13: 978-1416038979  In the last decade, the delineation of the human genome and the development of high throughput genomics and proteomics have transformed the practice of Pediatrics. The study of normal childhood growth and development, and pediatric diseases now focuses on the delineation of normal and abnormal gene expression, resultant cellular and organ responses, and the modification of such interactions by an increasing number of environmental factors. This is the second of two issues of the Pediatric Clinics of North America will provide an overview of the rapidly developing field of Pediatric Translational Medicine. New knowledge of basic molecular and developmental physiology and pathophysiology is rapidly being "translated" into new diagnostics and therapeutics for the practicing pediatrician. Rapid molecular diagnostics based on the identification of new disease genes, recognition of unique disease phenotypes at the cellular level, and the development of new therapeutic approaches based on pharmacogenomic profiling suggest that "individualized medicine" will soon be a possibility for every child. Combined with similar advances in epidemiology, bioinformatics, and population-based studies, Pediatric Translational Medicine will rapidly move from the laboratory bench to the patient bedside. These issues of the PCNA will be of value to all members of the pediatric health care delivery team, which now includes basic and clinical investigators. Further, it will provide students at all levels with a sense of the excitement which awaits their future development as tomorrow's Physician-Scientists. Contents: Preface Functional Genomics and Its Implications for Molecular Medicine Current Methods for the Rapid Diagnosis of Bioterrorism-Related Infectious Agents Human Artificial Chromosomes: Potential Applications and Clinical Considerations Inborn Errors of Development: Disruption of Pathways Critical for Normal Development Transcriptional Regulation of Perinatal Lung Maturation Renal Cystic Disease: New Insights for the Clinician Defects in Surfactant Synthesis: Clinical Implications The Cell Biology of Acute Childhood Respiratory Disease: Therapeutic Implications Pulmonary Hypertension in Children: The Twenty-First Century Molecular and Cellular Basis of Congenital Heart Disease The Molecular Basis of Pediatric Hypertension Reactive Oxygen Species Cerebral Autoregulation in Health and Disease - http://mihd.net/5wgk7m Labels: medical ebooks collection |
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